I worked with Neal on Friday, and we used a tool I haven’t worked with before- Monolingual. In this case we were cleaning up an Apple 10.5 computer to use as the base for an image that would then go to dozens (or maybe hundreds) of other computers. We wanted this base system to be as small and light as possible. Because the previous IT person had installed the system with support for additional languages (Assamese anyone?) the computer was bloated with these language files.
Running Monolingual removes the additional languages from the system, and from any other applications that may have also installed additional languages. In this case (admittedly an extreme case) running it saved over 3 GBs. Since the computers were being imaged using Netboot you can imagine the time and annoyance savings that 3GB times however many computers can bring. But really everyone should strive to have a lighter computer.